News: NC State on the Coast

2024/10/08 – NC State
NC State faculty and students are helping to keep coastal communities healthy through the North Carolina Center for Coastal Algae, People and Environment

NC C-CAPE (and our fearless leader Astrid Schnetzer) were featured on the NC State homepage.

NC C-CAPE was featured on the NC State homepage. Lots of information and quotes from folks in the center, including great photos of our colleagues in the field and laboratory. It is fun to contribute to such a large, meaningful research effort.

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“In the past few months, we’ve officially started to sample as NC C-CAPE,” [Barrett] Rose said. “It was a shock to see the magnitude of how much we were actually studying. It went from a small pilot study to a huge center effort.”

Data collection and analysis is only the first part of the work NC C-CAPE seeks to do. While harmful algal blooms are common in fresh waters across the U.S. and the world, major data gaps around the issue exist. [Astrid] Schnetzer’s data will inform NC C-CAPE’s other two projects, which focus on predicting the health risks of toxic algal blooms on mammals and humans, as well as considering how factors like climate change will affect future toxin levels in water and seafood.

“The most exciting aspect of NC C-CAPE for me is that the research doesn’t end where my expertise ends,” said Schnetzer. “What we learn from the field about algal toxins is handed to the next team to look at the bigger picture on the ecosystem level and in connection to human health.”

News: Oceans and Human Health Center

2024/03/19 – NCSU Civil, Construction, and Environmental Engineering
CCEE faculty to advance understanding of toxic algae blooms, protect human health as part of new NSF, NIEHS Center at NC State

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Obenour will lead a project with Dietrich and Natalie Nelson (Department of Biological and Agricultural Engineering) focused on the development of models to predict the transport of cyanotoxins — toxins produced by cyanobacteria released in algae blooms — in coastal environments. The models will focus on coastal North Carolina, especially the estuaries and sounds where freshwaters mix with saline waters. With the models, researchers will evaluate where cyanotoxins may collect and where they may originate. They will also evaluate scenarios of future climate, such as how changes in temperature, river flows, and sea levels may affect the transport of cyanotoxin.

According to Obenour, “the research will protect public health by identifying cyanotoxin hotspots and by informing management actions to reduce cyanotoxin risks in the future.”

2024/02/28 – NCSU College of Sciences
NC State Receives $6.9 Million From NSF, NIEHS to Fund New Oceans and Human Health Center

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NC C-CAPE will carry out three research projects. The goal of the first project is to understand the dynamics of harmful algal blooms and learn more about the presence and distribution of microcystin — a liver toxin — across the Pamlico-Albemarle Sound System, the country’s largest lagoonal estuary. They will then link spatiotemporal patterns to the contamination of seafood. The second project will define how microcystin mixtures influence mechanisms of liver toxicity in regulatory-relevant mammalian models and at-risk human populations. In the third project, researchers will work to predict microcystin distributions in water and seafood based on various environmental controls — and assess exposure risk in a changing climate. They will do so by integrating diverse data sets and coastal circulation modeling within a probabilistic modeling framework.

North Carolina Center for Coastal Algae, People, and Environment

The NC C-CAPE: North Carolina Center for Coastal Algae, People, and Environment will investigate the health effects of various microcystin (MC) mixtures, and it will elucidate links between environmental and climatic drivers and harmful algal bloom (HAB) dynamics, MC congener composition, and toxin contamination in oysters and blue crabs. We will determine and the health effects of MC-mixtures on hepatic toxicity, NAFLD and hepatocellular carcinoma in model systems and humans. The Center’s Community Engagement Core will use the principles of data justice to address HAB exposure and prevention, where community members are experts, rather than objects of research, and have the capacity to conduct critical and systemic inquiry into their own lived experiences. The Administrative Core will provide efficient and effective fiscal and scientific leadership and promote interactions and collaborations across all Center components and beyond. Project 1 will advance our understanding of HAB dynamics and MC contamination in seafood, combining state-of-the-art in situ observing technologies and targeted field surveys. In addition, experimental work will elucidate trophic transfer of toxins in oysters and blue crabs. Project 2 will define how MC mixtures influence mechanisms of liver toxicity and resulting risk of adverse health outcomes in regulatory-relevant mammalian models as well as at-risk human populations. Project 3 will integrate highly diverse data sets and coastal circulation modeling within a probabilistic (Bayesian) modeling framework to elucidate environmental controls on MC distribution in water and seafood and assess MC exposure risk in a changing climate. NC C-CAPE will provide significant insight to guide efforts to implement effective monitoring approaches, inform guideline values for safe consumption of water and seafood, deliver predictive tools to assess emergent and future toxin exposure risk, and will leverage community engagement initiatives to fill data gaps and improve oceans and human health.

A Schnetzer, SM Belcher, BB Cutts, DR Obenour, T Ben-Horin, JC Dietrich, C Hoyo, NG Nelson, R Paerl. “North Carolina Center for Coastal Algae, People, and Environment (NC C-CAPE).” National Institutes of Health, National Institute of Environmental Health Sciences, Centers for Oceans and Human Health 4: Impacts of Climate Change on Oceans and Great Lakes, 2024/02/01 to 2029/01/31, $6,913,382 (Dietrich: $467,482).